Around 100 firefighters are tackling a blaze in industrial units near the Chingford border.
Crews have brought the fire near the Banbury and William Girling reservoirs under control but remain at the scene.
The blaze, in Advent Way, Upper Edmonton, is not affecting traffic on the nearby North Circular.
Responding to a call at 3.08am, the fire brigade sent 15 fire engines and two cherry pickers to the scene.
No residential properties are affected and no injuries have been reported.
The cause of the fire is unknown at this stage.
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