Leyton Orient will be targeting another midweek win tonight when they host in-form Colchester United in League One.

The O's have won their last five matches under the evening lights and will be looking to maintain this run at Brisbane Road against their rivals.

Orient suffered a 2-0 defeat at Oldham on Saturday and once again manager Russell Slade is targeting a swift response from his players.

Slade, who could have Lee Cook available after he missed the last match with a virus, said: "The good thing about the squad is we bounce back and we're going to have to do it again.

"We've put ourselves in a situation where we need to bounce back and it's another tough home game against Colchester. We've got to put it right.

"Whoever you face at home the emphasis is on yourselves to be positive and go and get the three points and that's what we'll endeavour to do."

Colchester have hit form under their new manager Joe Dunne with four league wins from their last five taking them above Orient in the table.