Last meeting: Leyton Orient 1 Exeter City 1 (08-03-2003). This was not a match to head to the exits before the referee had blown for the end of the half. Lee Thorpe put the O's ahead on 45 minutes, only for Grecians striker Sean Devine to grab a last-gasp 90th-minute equaliser.
The opposition: Exeter went into the season on the high of back-to-back promotions after spending three years in the Conference. They finished as runners-up to Brentford in League Two last year.
Danger men: Veteran striker Marcus Stewart, formally of Ipswich Town and Sunderland, is still turning out for Exeter and recently scored his 250th career goal.
Prediction: Leyton Orient 2 Exeter City 2.
Did you know? The club are owned and run by its fans, through the Exeter City Supporters Trust, who took over following their relegation to the Conference.
Midweek: The O's have another week off before travelling to Stockport County on Saturday, September 19.
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