A point was the reward against the promotion chasers tonight, but Orient may reflect with disappointment on the haul.
The result lifts Orient one place up the table into 16th place.
A explosive start to the match with three goals inside the opening 15 minutes saw the hosts take the lead.
Scott McGleish and then Terrell Forbes hit the net for the hosts in the early stages.
It came after Stephen Gleeson stunned the Matchroom with his angry long range drive that blasted The Dons in front with just four minutes gone.
Orient slipped back after that and the game turned into a even affair with chances at a premium for both teams.
But the Dons, chasing promotion out of League One, responded sharply after half time.
Substitute Sean O'Hanlon marked his entry to the fray with the equaliser on 56 minutes.
A point will do for Orient, but more seemed on the cards when veteran McGleish and then Forbes struck.
McGleish showed a team is most vulnerable when it has just scored a goal, by stroking Jimmy Smith's pass low into the far corner from the edge of the area on nine minutes.
Anti goal machine Terrell Forbes sealed an amazing opening period with his header, goal three of the game on 14 minutes.
He connected with Daniels' corner to lift himself onto personal best-ever figures: two goals for the campaign so far.
But the Dons came out the hungerier after half-time.
Orient in contrast were sloppy at the back in the face of the sharper Dons.
The equaliser was coming and it duly did when Jimmy Smith conceded a soft foul on Dean Lewington near the touch line.
Peter Leven dipped the free-kick over to the near post and half sub Sean O'Hanlon tucked it inside the post with his head.
Ibehre drew fine diving save from the stopper on the stroke of half-time when he flicked on Gleesson's bending shot.
The ex-O drew ironic cheers from home fans for his wayward shooting.
Now Orient gear up for Swansea.
Jones (gk), Whing, Chorley, Forbes, Cox (Mpoku 75), Dawson (Kane 39), McGleish (Téhoué 68), Revell, Daniels, Spring, Smith.
Unused subs: Butcher (gk), Jarvis, Argent, Odubajo.
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