Russell Slade has kept faith with the side that lost here at Brisbane Road to Tranmere Rovers on Saturday, naming the exact same squad.
The news means captain Stephen Dawson continues to get the minutes needed in midfield as he returns from his ankle injury.
Jamie Cureton will lead the line alongside former Wycombe striker Alex Revell as the O’s go in search of their first league goals of the season.
Lee Butcher continues between the sticks following the news that Jamie Jones could be out for up to six months, but Slade has again opted not to name a replacement stopper.
On the bench, Terrell Forbes, Marc Laird and David Mooney are all fit enough to be considered for action.
Orient: Butcher; Omozusi, Chorley, Cuthbert, Daniels; Smith, Spring, Dawson, Cox; Revell, Cureton.
Subs: Forbes, Porter, Laird, Richardson, Mooney.
Wycombe: Bull; Foster, Winfield, Tunnicliffe, Sandell; Ainsworth, Halls, Donnelly, Grant; Strevens, Beavon.
Subs: Johnson, Harding, Rendell, Bloomfield, Benyon.
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